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Nigel Plummer PhD

Probiotics and the Gastrointestinal Tract

The human gastrointestinal (GI) tract has co-evolved with a very complex, stable microbial population (known as the gut microbiota) of more than 100 trillion (100,000,000,000,000) microorganisms comprising several hundred different species that has led to the development and optimization of complex immune mechanisms that control this ecosystem.

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Probiotics And Atopic Eczema: A Double-Blind Randomised Controlled Trial

SJ Allen, 2S Jordan, 1M Storey, 1CA Thornton, 1MB Gravenor, 3I Garaiova, 1RH Jones, 1TV Macfarlane, 1AL Seager, 1B Manshian, 1M Moller, 1M Omakobia, 3SF Plummer,4DWang,1GMorgan 1CollegeofMedicine,SwanseaUniversity,Swansea, UK; 2College of Human and Health Sciences, Swansea University, Swansea, UK; 4Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK

Atopic disorders are common in young children. The development of atopy may be influenced by exposure to microbes in early life. We tested the hypothesis that admin- istration of a multi-strain probiotic during pregnancy and to young infants would prevent atopy in childhood. read more…

Human Strain Differentiation in Probiotics

Dr. Nigel Plummer, PhD, Pharmax

Probiotics are live “friendly” microflora found in the intestinal tract that These microflora work to reduce the amount of harmful bacteria, while replenishing and maintaining the helpful strains. Lifestyle, travel, age, illness, stress, digestive disorders, diet, antibiotics, and other medication can deplete the body’s reserves of microflora needed to maintain optimal intestinal health. While probiotic supplements that aid in creating these beneficial microflora read more…

Probiotics and the Gastrointestinal Tract

Nigel Plummer PhD and Sue Plummer PhD

What is a probiotic?
For centuries living microorganisms, particularly lactic acid bacteria (producers of lactic acid from sugar) have been used in food preservation so there has been a long term awareness of the beneficial effects of microorganisms. However, the first reports of beneficial effects on human health linked to lactobacilli and bifidobacteria appeared in the late 19th/early 20th century (Tannock, 2003). read more…

Video: Dr Nigel Plummer talks about Swansea Baby Trial

Watch this video that discusses immune health with probiotics and children. A probiotic study on allergy in children.

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