As we head into 2014, what are the health conditions appearing most prominently on the radar of consumers, researchers, and even governments? What new ingredients are seeing promising clinical study results? And what old standby supplements are no longer performing as well as they used to?
As working Americans are pushed by employers to do more with less, Baby Boomers continue to grow older, and everyone suffers from the everyday stress of life, several health conditions have surged to the forefront of clinical research. Read on to discover more about how consumer interest in brain cognition, sleep disorders, stress relief, read more…
Sivarama Prasad Vinjamury, MD (Ayurveda), MAOM; Betsy B. Singh, PhD; Raheleh Khorsan, MA; Rocky Comberiati, DC; Melany Meier, DC; Susan Holm, MS, DC
Temporomandibular disorders (TMD), or craniomandibular disorders (CMD), is a collective term used to describe a group of cranio-oro-facial conditions that are differentiated as pain or noise in the mastication muscles or temporomandibular joints (TMJ) and limited mandibular function.1 TMD pain can simulate atypical facial pain (AFP) with characteristics of pain ranging from unilateral, bilateral, or migratory.2-6 More than 10 million people in the United States suffer from TMD.2,3 The average age of onset is between 18 read more…
Angela L. Drury, DPM, FACFAS
Patients suffering from neuroma pain describe their pain as intense, usually 8 to 10 out of 10 on a numerical pain-rating scale. Neuroma pain debilitates a patient’s activity level. It is difficult for patients to wear closed-toe shoes, and most often patients cannot stay active in a healthy exercise program due to the pain. This is a common foot complaint of patients presenting to a podiatrist’s office.
A 70-year-old female presented to the clinic with a possible neuroma. Her constant pain was 8 to 10 on the pain scale; her pain was read more…
Differential metabolic effects of glucosamine and Nacetylglucosamine in human articular chondrocytes
Alexander R. Shikhman, Diana C. Brinson, Jean Valbracht and Martin K. Lotz
Objective—Aminosugars are commonly used to treat osteoarthritis; however, molecular mechanisms mediating their anti-arthritic activities are still poorly understood. This study analyzes facilitated transport and metabolic effects of glucosamine (GlcN) and N-acetylglucosamine (GlcNAc) in human articular chondrocytes.
Methods—Human articular chondrocytes were isolated from knee cartilage. Facilitated transport of glucose, GlcN and GlcNAc was measured by uptake of [ 3H]2-deoxyglucose, [ 3H]GlcN and [ 3H] GlcNAc. Glucose transporter (GLUT) expression was analyzed by Western blotting. Production of sulfated glycosaminoglycans (SGAG) was measured using [ 35 S]SO4. Hyaluronan read more…