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The Clinical Importance Of Vitamin D (Cholecalciferol): A Paradigm Shift With Implications For All Healthcare Providers

Alex Vasquez, DC, ND, Gilbert Manso, MD, John Cannell, MD

Abstract
While we are all familiar with the important role of vitamin D in calcium absorption and bone metabolism, many doctors and patients are not aware of the recent research on vitamin D and the widening range of therapeutic applications available for cholecalciferol, which can be classified as both a vitamin and a pro-hormone. Additionally, we also now realize that the Food and Nutrition Board’s previously defined Upper Limit (UL) for safe intake at 2,000 IU/day was set far too low and that the physiologic requirement for vitamin D in adults may be as high as 5,000 IU/day, which is less than half of the >10,000 IU that can be produced endogenously with full-body sun exposure.1,2 With the discovery of vitamin D receptors in tis- sues other than the gut and bone—especially the brain, breast, prostate, and lymphocytes—and the recent research suggesting that higher vitamin D levels provide protection from diabetes mellitus, osteoporosis, osteoarthritis, hypertension, cardiovascu- lar disease, metabolic syndrome, depression, several autoimmune diseases, and cancers of the breast, prostate, and colon, we can now utilize vitamin D for a wider range of preventive and thera- peutic applications to maintain and improve our patients’ health.3 Based on the research reviewed in this article, the current authors believe that assessment of vitamin D status and treatment of vita-

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This entry was posted in Articles, Integrative Medicine Clinicians Journal, Nutrition/Vitamins/Minerals/Dietary Supplements, Nutritional Medicine, Supplement Science, Vitamin D and tagged , . Bookmark the permalink. Follow any comments here with the RSS feed for this post.
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