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Tag Archives: Hypersensitivity Testing

Hypersensitivity Reactions and Methods of Detection

David Marc, B.Sc.a, & Kelly Olson Ph.Da.

Hypersensitivity reactions are classified into four groups (Type I, II, III, and IV), each characterized by specific biological actions. Research has focused on understanding each hypersensitvity to ensure appropriate therapeutic recommendations are made. This overview will present the defining characteristics of each hypersensitivity and examine the diagnostic methods used to determine the existence of a specific type. Type I hypersensitivities can be determined by provacation testing, immediate-type skin testing, or radioallergosorbent tests (RASTs); Type II hypersensitivities can be determined by measuring the level of IgG antibodies to specific host proteins; Type III read more…

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