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Daxitrol: A Novel Approach for Controlling Cravings

David Marc, B.Sc. , & Kelly Olson Ph.D .

Cravings are defined as an intense drive or desire directed towards food, drugs, gambling, and other stimuli. The pleasure/reward and motivational pathways associated with cravings involve multiple neurotransmitters including dopamine, glutamate, serotonin, acetylcholine, and various peptides. These neurotransmitters also serve as therapeutic targets to modulate the pleasure/reward pathway. Daxitrol is a novel product that contains L-3,4-dihydroxyphenylalanine (L-DOPA), epigallocatechin gallate (EGCG), N-acetylcysteine (NAC), 5-hydroxytryptophan (5- HTP), L-phenylalanine, forskolin, and huperzine A (HupA) to manage cravings and enhance self-control. This overview will present the neurological pathways that underlie cravings and propose the read more…

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