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Avipaxin and Modulation of the Immune System

White paper by David Marc, M.B., Deanna Fall, B.A. & Kelly Olson Ph.D

This white paper reviews the role of the cholinergic immune regulating pathway and a pilot study using the supplements containing huperzine A (HupA), L-alpha-glycerylphosphorylcholine (α-GPC), and acetyl-L-carnitine. The primary function of the cholinergic immune-regulating pathway is to attenuate systemic expression of certain cytokines following an innate immune response (Tracey, 2009). The cholinergic immune-regulating pathway is a reflex pathway, which functions to reestablish homeostasis and prevent systemic immune activation. read more…

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Avipaxin and Modulation of the Immune System

David Marc, M.B. , Deanna Fall, B.A. & Kelly Olson Ph.D .

Abstract
Avipaxin is a dietary supplement that contains huperzine A (HupA), L-alpha-glycerylphosphorylcholine (α-GPC), and acetyl-L-carnitine to support acetylcholine levels and function. HupA is a powerful central nervous system (CNS) acetylcholinesterase (AChE) inhibitor and has been proposed as a natural agent to promote healthy immune system function. α-GPC is a natural choline compound, and acetyl-L-carnitine acts as an acetyl donor to support the synthesis of acetylcholine. The immunomodulatory effects of Avipaxin may be mediated by support of acetylcholine levels and activity. Avipaxin appears to regulate systemic immune activation by read more…

Also posted in Articles, Autonomic Nervous System, Cognitive Health, Immune Health, Neuro Endo Immune Learning Center, Neurological, Neurotransmitters, Nutritional Medicine | | Also tagged , , , Leave a comment
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