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Salacia spp: Hypoglycemic Principles and Possible Role in Diabetes Management

Amritpal Singh, MD Ayurveda; and Sanjiv Duggal, MSc

The salacia species (Celastraceae), including S chinensis, S reticulata, and S oblonga, are used as antidiabetic agents in traditional systems of medicine such as Ayurveda and Unani. The plants have been used in India, Japan, and Korea to treat high blood glucose levels. Preclinical investigations have demonstrated antiobesity activity of salacia, warranting large-scale clinical studies. Isolated clinical trials have, thus far, supported this claim. This review summarizes pharmacological investigations of various species of salacia with respect to diabetes.

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