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Oxidative Stress In Autism by Woody R. McGinnis, MD


Woody R. McGinnis, MD

When oxidants exceed the antioxidant defense, biological systems suffer oxidative stress, with damage to biomolecules and functional impairment. Autism is a behavioral disorder, with hallmark communication and social deficits. It has been suggested that oxidative stress may play a role in the pathophysiology underlying the behaviors that define autism.1 Another serious behavioral disorder, schizophrenia, features high oxidative biomarkers2 and documentation of clinical response to antioxidant.3 Many neuroleptic medications used in the treatment of schizophrenia are, in fact, potent antioxidants.4

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