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Improvement Of Gastroesophageal Reflux Disease After Initiation Of A Low-Carbohydrate Diet: Five Brief Case Reports

William S. Yancy, Jr, MD, MHS, Dawn Provenzale, MD, MSPH, and Eric C. Westman, MD, MHS

Heartburn (pyrosis) and gastroesophageal reflux symptoms are common complaints encoun- tered in outpatient medical clinics.1 It is esti- mated that up to 40% of adults in the United States have occasional heartburn (approximate- ly once a month) and up to 10% experience daily heartburn.2,3 In addition, these symptoms have a substantial effect on health-related quality of life (QOL); in some studies, QOL can be impaired as severely as with angina or heart failure.4 Medications used to treat these symptoms have been among the most frequently prescribed medications in the United States in recent years. In fact, 2 medications commonly used for gastroesophageal reflux disease (GERD) rank among the top 5 medications of 1999 in terms of dollars spent.

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